The pharmaceutical company Mylan is facing more po Essays - Biology

The pharmaceutical company Mylan is facing more po Essays - Biology The pharmaceutical company Mylan is facing more political pressure to confront the price hike of EpiPen after 20 US senators, including Elizabeth Warren and Bernie Sanders, sent an open letter on Tuesday to the company criticising its "exorbitantly expensive" price hikes. Reports emerged last week that the company had implemented a series of gradual price increases inflating the price of the drug from $56.64 to $317.82, a 461% increase in cost since Mylan acquired the rights to EpiPen in 2007. During that same time, Heather Bresch, chief executive officer of Mylan, saw her pay rise $2,453,456 to $18,931,068 , a 671% increase . Last week, she sold 100,200 of her shares in the company for more than $5m. EpiPen CEO hiked prices on two dozen products and got a 671% pay raise "The EpiPen auto-injector delivers a life-saving dose of epinephrine to patients suffering from anaphylaxis. Anaphylactic shock can lead to serious injury or death if untreated; thus, making sure the EpiPen is readily available for use is a critical part of life for millions of Americans living with severe allergies," the Democratic senators wrote in the eight-page letter addressed to Bresch. "The EpiPen, however, has become so exorbitantly expensive that access to this life-saving combination product is in jeopardy for many Americans. "Mylan's near monopoly on the epinephrine auto-injector market has allowed you to increase prices well beyond those that are justified by any increase in the costs of manufacturing the EpiPen," the senators wrote. The senators gave Bresch a deadline of 12 September to address seven multi-part questions about the company's "Savings Card" for customers with insurance, patient assistance program, school programs and plans to release a cheaper generic version of the EpiPen in several weeks. They were sceptical of the company's attempts to defuse the row, noting that the price of the planned generic "is still three times higher than the cost of the branded EpiPen in 2007". Democratic senators Tammy Baldwin, Richard Blumenthal, Barbara Boxer, Sherrod Brown, Joe Donnelly, Richard J Durbin, Al Franken, Heidi Heitkamp, Mazie K Hirono, Amy Klobuchar, Patrick Leahy, Edward Markey, Chris Murphy, Jack Reed, Brian Schatz, Jon Tester, Tom Udall and Sheldon Whitehouse also signed the letter. Last week, Hillary Clinton commented on the controversy, announcing a plan to reduce drug price increases . In it, the Democratic presidential nominee wrote that manufacturers "should be required to explain significant price increases, and prove that any additional costs are linked to additional patient benefits and better value". She called on Mylan to reduce the price "immediately". Other lawmakers have already written open letters to both Bresch, who is the the daughter of West Virginia senator Joe Manchin, and the Food and Drug Administration. Senators Susan Collins and Claire McCaskill sent a request for information to Bresch from the Committee on Aging. Iowa senator Chuck Grassley and others asked the FDA for suggestions on " alternatives to the EpiPen ". Connecticut senator Richard Blumenthal sent his own letter in addition to the letter sent on Tuesday. "My office has been contacted by dozens of concerned Connecticut residents, families, and first responders who urgently require your life-saving product but fear that its skyrocketing price has put it out of reach," Blumenthal wrote last week. The Guardian has reached out to Mylan for comment. Genetically Modified Babies BERKELEY, Calif. AN advisory committee of the Food and Drug Administration is set to begin two days of meetings tomorrow toconsider radical biological proceduresthat, if successful, would produce genetically modified human beings. This is a dangerous step. These techniques would change every cell in the bodies of children born as a result of their use, and these alterations would be passed down to future generations. The F.D.A. calls them mitochondrial manipulation technologies. The procedures involve removing the nuclear material either from the egg or embryo of a woman with inheritable mitochondrial disease and inserting it into a healthy egg or embryo of a donor whose own nuclear material has been discarded. Any offspring would carry genetic material from three people the nuclear DNA of the mother and father, and the mitochondrial DNA of the donor. Roughly 1,000 to 4,000 children born in the United States each year will develop

Indie Attitude

Indie Attitude While I’m on a Joel Friedlander high (last week’s issue), I had to sink my teeth into a piece he had on his blog recently. thebookdesigner.com/2014/05/the-secret-sauce-for-indie-publishers-attitude/ The blog post was titled The Secret Sauce for Indie Publishers: Attitude. Nina Amir was the author of that post, and she advised that an Indie attitude needed to consist of: 1) Willingness 2) Optimism 3) Objectivity 4) Tenacity I loved reading the comments afterwards, some from readers who obviously were not interested in an attitude adjustment, preferring to remain in their I-can’t-do-this or you-have-to-know-somebody mindset. Actually, the Indie attitude is just a healthy attitude toward life. You don’t have to be a writer, and your attitude doesn’t have to be about writing. And if you want to take attitude and   boil it down to one word, you can stop with the first in Nina Amir’s list: WILLINGNESS. If you are willing to do whatever it takes to change, try new things, learn new ways, attempt trial and error, and write until you figure out how to play this game and make a living at it, it just might happen. I had a long conversation with my editor the other day about more books, a new series, and how I view my writing career. In the exchange, I let her know that whether I’m published or not, I’ll write my stories. And if I cannot find a publisher, I’ll self-publish. It’s just what I do, and I’ll adapt to whatever I need to in order to keep doing what I’m doing. She was impressed at my â€Å"attitude† toward the future.  Frankly, I see my future no other way. Why not be willing to adapt . . . when it makes me better or more successful? Why not learn new ways . . . if old ones have quit working? Why not step outside my comfort zone . . . if staying inside it confines me to a routine that isn’t moving me forward? It’s all attitude. You’ve met those people in your life, the ones with a great outlook and a willingness to improve. They are exciting to be around. So why can’t that be you?

Religion in Vietnam Research Paper Example | Topics and Well Written Essays - 2000 words

Religion in Vietnam - Research Paper Example This topic is likely to be tremendously engrossing and enjoyable to read. This is because it will evaluate the hypothesis in procedures that will lead to the final conclusion. One must support this statement that science must destroy religion since it makes sense. Science is an intellectual activity that humans carry out to discover information concerning the natural world, and ways of organizing information into meaningful patterns. Religion refers to a collection of beliefs, worldviews, and cultural systems that relate humanity to spirituality and moral values (Harris 12). These are two different fields that guide people in making various conclusions in life. The main idea in this essay is an analysis of religion and science that people use to form reasonable claims that help them understand the universe and human beings. It critically analyses the misleading aspect of religion that is used to make people believe various propositions that cannot happen in the real world. It explains the main differences between science and religion giving a deeper explanation behind the success of religion. This forms the thesis statement since it expounds on the irreco ncilable commitments of religion that amount to human conflict (Harris 34). It explains that our fear of provoking religion makes us incapable of criticizing ideas that maladaptive and absurd.... The arrival of the French missionaries in Vietnam in the 17th century was to have an effect on how people worshipped and how they talked to their god (Fox, 5). This is because their influence profoundly affected the manner in which Vietnam developed several years later. â€Å"Vietnamese society during the 17th and 18th centuries experienced many vicissitudes and complexities that created favourable conditions for the development of Christianity†(Fox,1). This is not only in the religious conviction but in addition in the political systems. This is because it was part of the cause of the Vietnam War that its effects have continued to be experienced until the recent past. Even, though, the missionaries received a warm welcome from the local population, this waned away after the realization that the missionaries had stated to recruit the population into their own religion. This is one of the chief reasons that lead to the conversion of Buddhists to Christianity and its expansion. The local population’s religion was to be transformed from Buddhism to Roman Catholicism for ease of governance. This is because, within the missionaries, there were explorers who determined the place to be a most favorable site to expand its empire. Threfore, the local population was encouraged to abandon their traditions and be loyal to God and not to the Emperor on conversion to Catholicism. This received a boost when French troops were sent to protect the missionaries, for they had been cases of frequent murders of catholic priests. This reinforcement and the subsequent surrender of Vietnam emperor allowed for continued conversion of the local population. The efforts of China to drive out the French troops from Vietnam that were thwarted by the French Army's

Constitution short paper Essay Example | Topics and Well Written Essays - 500 words

Constitution short paper - Essay Example Even though the federal government has the power to conduct war, control international trade, monitor drug abuse, it cannot survive without the full support of the state government .For instance, Let us assume that I am a lawyer and has to present a criminal case against a drug addict who has killed a man on the street in an attempt to steal his wallet. Here I am subjecting the case to the judge, who is the part of state government. I am not taking my case initially to the federal government. The crime has happened in a specific state, let us assume in Texas and I am obviously being approached for advocacy from the victim side from the state of Texas. My main assistance here would be the police department of Texas, which comes under the rule of state government of Texas. In this criminal case, I would put forward some prominent points which would be deeply judgmental in offending the drug addict against the murder of my client. But I cannot collect any legal points without the support and forensic evidence of the state police department of Texas. The first procedure in any criminal case is the witnessing of police with regard to the nature of crime and the evidence the criminal have left in the crime vicinity. So here, I can strongly establish that the primary support I get should be from the state government as the police department fall under the power limit of state government. No lawyer can plan an advocacy without the forensic evidence and records of police department. Here it is obvious that the state department’s stand is more needed and their power is more usable in order to win the criminal case of drug addict. It is a known fact, that the clause of the cases related to this specific criminal case is charted in the constitution of Federal government. However the rest of the matters related to the defending of the victim are tied up to the

Implications of Research on Bilingual and Polyglot Aphasia :: Essays Papers

Implications of Research on Bilingual and Polyglot Aphasia Research conducted on bilingual and polyglot aphasics has brought interest into the field of linguistics mainly because of its contribution to L2 research, especially in providing explanations for the organization of distinct languages in the brain. Since there exists such a variation between individual cases, the most important thing to come out of this research is a set of factors involved in these aphasia cases as well as theories emerging from research. Some of these factors include: the language environment in which the aphasic recovers, influence of the L1, language mixing, brain lateralization for language, and the question of whether structurally similar languages follow a similar pattern of deficits and recovery. The main pathological implication—determining what is missing or misplaced inside a bilingual or polyglot aphasic’s brain—also shares importance with determining how different languages are structured in the brain. The history of research on bilingual aphasia into the 20th century begins with the work of two Frenchmen at the end of the 19th century by the names of Ribot and Pitres. Ribot wrote his paper, Les maladies de la memoire, in 1881 (Lebrun 12). Pitres, using seven polyglot aphasic patients as the basis for his work, published Etude sur l’aphasie des polyglottes in 1895 (Lebrun 11). Ribot’s conclusion about recovery in polyglot aphasics is known as Ribot’s rule, which basically states that L1 will recover more than any L2’s. Pitres’ rule, built off of Ribot’s, takes a different approach in saying that the language used most often â€Å"pre-morbidly†(i.e. before the onset of aphasia) is the one which will be regained the fullest, irregardless of that language being an L1 or L2. Various individual cases have cropped up which match both theories, so further research has attempted to explain variances in recovery of specific languages through other means. Also, after Pitres, the research focus became more one of examining deficits in syntax and morphology in an attempt to explain brain construction, and less of an analysis of â€Å"interesting language recovery† in these patients. Examining Theoretical Issues Another important component of the study of polyglot aphasia came with the distinction between compound and co-ordinate bilingualism, as examined by Lambert and Fillenbaum (1959). Although the state of being a â€Å"bilingual† is a hazy one, the distinction between the two concepts comes with the context of acquisition.

I Would Like to Be Remembered

Do you want to know what teenagers worry about the most? I feel like teenagers worry about either relationships or appearances. I worry about a lot of things like my grades, relationships, family, friends, and my education. I worry about my grades because I want to have an awesome G. P. A and I want to go to college. Relationships are one of the things I worry about because I feel like If I get Into a relationship It would go wrong. Also I feel like I would regret getting Into one with that person. I worry about family and friends the most because they are my number one poorly In fife.My motto Is family and friends before anything and anyone. The reason I worry about my education is because I want to the University of Los Angels California or Norfolk State university when I graduate high school. That Is my mall goal which Is to graduate and go to a nice college of my choice or with a scholarship. School and family are the main things that I worry about the most and I will always worr y about school until I am done. I will always worry about my family and friends. My best friend is India Gregory. She is my best friend because she was one of the arils that helped me find my classes on my first day at Semiskilled.We have that type of bond like I consider her my sister and whenever we are on the phone she talks to my sister too. We all joke around and Joke each other. We tell each other everything it does not matter what it is. I do think that our friendship will last after high school. We are unbreakable. Yes, India has influenced me. One day we were on the phone and I told her about my relationship problems. I would stay in a relationship even though I was not happy with that person. She told me that it can affect me more because I would be hurt hill I was pretending to still like this person.So she taught me to love myself before I love anybody. She is my best friend for life because she is the one girl that I can see myself hanging out with out with in my adult years. We have been through a lot with girls trying to break up our friendship. One thing that they do not know is that we will never stop being friends. It does not matter what happens I would choose her over anything. She is like my blood sister. Blood is thicker than water. I love her with all my heart I Would Like to Be Remembered By Pià ±atas re one of the things I worry about because I feel like if I get into a relationship it would go wrong.Also I feel like I would regret getting into one with that person. I worry about family and friends the most because they are my number one priority in life. My motto is family and friends before anything and anyone. The reason I worry about my education is because I want to the University of Los Angels California or Norfolk State University when I graduate high school. That is my main goal which is to my sister too. We all Joke around and Joke each other. We tell each other everything it

French Accent Homographs

You may not realize it, but French accents have a purpose. While some accents just signify that an S used to follow that vowel in Old French (e.g., à ©tudiant used to be spelled estudiant), most French accents indicate the correct pronunciation of the letter they modify. In addition, there are dozens of French word pairs which are spelled (though not always pronounced) the same other than accents. To avoid confusion, you should always distinguish between these words by using the correct accents. Note: It is grammatically acceptable to leave accents off capital letters. However, since missing accents may cause confusion in pronunciation and meaning and are technically spelling mistakes, I feel that one should always write with accents. a - third person singular of avoir (to have)à   - (preposition) to, at, inacre - acreà ¢cre - (adjective) acrid, pungentà ¢ge - ageà ¢gà © - (adjective) oldaie - first person singular subjunctive and second person singular imperative of avoiraà ¯e - (interjection) oucharrià ©rà © - (adjective) overdue, backward; (noun) backlog, arrearsarrià ¨re - back, stern, rear, aftbronze - bronze objectbronzà © - past participle of bronzer (to tan, bronze)à §a - (indefinite demonstrative pronoun) that, ità §Ãƒ   et là   - here and therecolle - gluecollà © - past participle of coller (to glue)congres - eelscongrà ¨s - conference, congresscote - quotation, quoted value, ratingcotà © - highly thought of / rated (past participle of cà ´ter)cà ´te - rib, slope, coastlinecà ´tà © - sidecrà ªpe - crepe (thin pancake), crepe papercrà ªpà © - past participle of crà ªper (to backcomb, crimp)cure - cure, treatmentcurà © - priest; past participle of curer (to clean out)de - (preposi tion) of, fromdà © - thimble, diedes - (indefinite article, partitive article) some; contraction of de lesdà ¨s - (preposition) fromdiffà ©rent - differentdiffà ¨rent - third person plural conjugation of diffà ©rer (to differ)du - contraction of de ledà » - past participle of devoir (to have to)-e vs à ©At the end of -er verbs, the accent is the difference between the first and third person singular present tense and the past participle-e - à ©tudie, parle, visite-à © - à ©tudià ©, parlà ©, visità ©entre - (preposition) betweenentrà © - past participle of entrer (to enter)es - second person singular of à ªtre (to be)à ¨s - contraction of en lesà ªtes - second person plural of à ªtreà ©tà ©s - summerseut - third person singular passà © simple of avoireà »t - third person singular imperfect subjunctive of avoirferme - farmfermà © - past participle of fermer (to close)fut - third person singular passà © simple of à ªtrefà »t - third person singular imperfe ct subjunctive of à ªtre gà ¨ne - genegà ªne - trouble, bother, embarrassmentgà ªnà © - (adjective) short of, embarrassed; past participle of gà ªner (to bother) grade - rank, degreegradà © - officerhaler - to haul inhà ¢ler - to tanillustre - illustrious, renownedillustrà © - illustratedinfecte - (fem adjective) revolting, filthy, obnoxiousinfectà © - infected, contaminatedinterne (adj) internal, inner; (noun) boarder, interninternà © - inmate (of a mental hospital), internee (politics)jeune - (adjective) youngjeà »ne - fastingjuge - judgejugà © - past participle of juger (to judge)la - (definite article) the; (direct object pronoun) her, itlà   - (adverb) therelevà © - survey; past participle of lever (to lift, raise)là ¨ve - first and third person singular of lever (applies to many stem-changing verbs)liquide - liquidliquidà © - past participle of liquider (to settle, pay; to liquidate, sell off; [inf] to finish off)mais - (conjunction) butmaà ¯s - cornmarche - walking, step, stairmarchà © - market; past participle of marcher (to walk, march; to work)masse - massmassà © - past participle of masser (to assemble, mass, group)ma t - checkmate; (adjective) matte, dullmà ¢t - mast, polemater - to subdue; (familiar) to ogle; to caulk; (familiar noun) mom, mummà ¢ter - to mastmà ©mà © - (baby talk) grannymà ªme - (adverb) samemeuble - piece of furnituremeublà © - (adjective) furnishedmodelà © - contours, relief; past participle of modeler (to model, shape, style, mold)modà ¨le - model, designmur - wallmà »r - (adjective) ripenotre - (possessive adjective) ournà ´tre - (possessive pronoun) oursnuance - shade, hue, slight difference, nuancenuancà © - (adjective) qualified, balanced, nuanced; past participle of nuancer (to shade, qualify, nuance)ou - (conjunction) oroà ¹ - (adverb) wherepà ¢te - pastry, paste; pà ¢tes - pastpà ¢tà © - pà ¢tà ©pà ©chà © - past participle of pà ©cherpà ªche - peach, fishingpà ©cher - to sinpà ªcher - to fishpà ©cheur - sinnerpà ªcheur - fishermanprà ªte - (feminine adjective) readyprà ªtà © - past participle of prà ªter (to lend)rate - spleenratà © - p ast participle of rater (to fail, miss)relà ¢che - rest, respiterelà ¢chà © - loose, laxreste - rest, leftoverrestà © - past participle of rester (to stay)retraite - retreat, retirementretraità © - retired person; past participle of retraiter (to reprocess)rot - belch, burprà ´t - (archaic) roastroue - wheelrouà © - (adj) cunning, sly; un rouà © - cunning/sly person; past participle of rouer (to beat/thrash)roule - first and third person singular of rouler (to wheel/roll along)roulà © - curved, rolledsale - dirtysalà © - saltysinistre (adj) gloomy, sinister; (m noun) accident, disaster, damagesinistrà © (adj) stricken, devastated; (m noun) disaster victimsublime - sublimesublimà © - sublimatedsuicide - act of suicidesuicidà © - victim of suicidesur - (preposition) onsà »r - (adjective) suretache - mark, spot, staintà ¢che - taskvalide - able-bodied, fit, validvalidà © - validatedvide - emptyvidà © - worn out; past participle of vider (to empty; to wear out)votre - ( possessive adjective) yourvà ´tre - (possessive pronoun) yours